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Weight loss is a goal that many individuals strive for in order to improve their overall health and well-being. While diet and exercise are commonly recommended methods for achieving weight loss, some people may have difficulty losing weight through these traditional means. In recent years, there has been growing interest in the use of weight loss drugs to help individuals achieve their weight loss goals. One such drug that has been gaining attention is semaglutide, a medication originally developed to treat type 2 diabetes.
Understanding Semaglutide
Semaglutide is a medication that belongs to a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists. These medications work by mimicking the effects of a hormone called GLP-1, which helps to regulate blood sugar levels and appetite. By activating GLP-1 receptors in the body, semaglutide can help to increase feelings of fullness, reduce appetite, and lower blood sugar levels.
In addition to its effects on appetite and blood sugar levels, semaglutide has also been found to promote weight loss in individuals who are overweight or obese. Studies have shown that individuals taking semaglutide for weight loss can experience significant reductions in body weight, BMI, and waist circumference.
One of the key benefits of semaglutide is its ability to help individuals achieve sustainable weight loss. Unlike fad diets or other quick-fix weight loss solutions, semaglutide works by addressing the underlying hormonal imbalances that can contribute to weight gain. By helping to regulate appetite and blood sugar levels, semaglutide can support long-term weight management and improve overall health.
Potential Side Effects
While semaglutide has shown promise as a weight loss medication, it is important to be aware of the potential side effects associated with this drug. Common side effects of semaglutide may include nausea, vomiting, diarrhea, and constipation. These side effects are typically mild to moderate in severity and may improve over time as the body adjusts to the medication.
In some cases, semaglutide may also increase the risk of more serious side effects, such as pancreatitis or thyroid tumors. It is important for individuals considering semaglutide for weight loss to discuss the potential risks and benefits with their healthcare provider before starting treatment. Your doctor can help you weigh the potential risks against the benefits of semaglutide and determine if this medication is right for you.
Overall, semaglutide has the potential to be a valuable tool in the treatment of obesity and overweight. By helping to regulate appetite, blood sugar levels, and body weight, semaglutide can support sustainable weight loss and improve overall health. However, it is important to use this medication under the guidance of a healthcare provider and to be aware of the potential side effects associated with its use.
Conclusion
Semaglutide is a promising weight loss medication that works by mimicking the effects of a hormone called GLP-1. By helping to regulate appetite, blood sugar levels, and body weight, semaglutide can support sustainable weight loss and improve overall health. While semaglutide may be an effective tool for some individuals struggling with obesity or overweight, it is important to be aware of the potential side effects associated with this medication. By working closely with a healthcare provider, individuals can determine if semaglutide is the right choice for their weight loss journey.
Ultimately, semaglutide offers a new option for individuals looking to achieve their weight loss goals. By addressing the underlying hormonal imbalances that can contribute to weight gain, semaglutide may help individuals achieve long-term weight management and improve their overall health and well-being.
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My guest is Dr. Herman Pontzer, Ph.D., a professor of evolutionary anthropology and global health at Duke University, known for his research on human bioenergetics, particularly energy expenditure and the exercise paradox. We discuss his work comparing highly active hunter-gatherer groups to more sedentary cultures, exploring their total energy expenditure and the surprising similarities. We examine the impact of factors such as age, sex, exercise, and pregnancy on daily energy expenditure. We also break down whether diet or exercise plays a greater role in weight management and weight loss. Additionally, we explore how genetics and the environment interact to shape human physiology, highlighting how population-level findings often overlook individual variation and emphasizing the need for medical and diagnostic practices to account for this diversity. Read the full episode show notes: https://go.performpodcast.com/FAtfelj *Thank you to our sponsors* AG1: https://drinkag1.com/perform David Protein: https://davidprotein.com/perform LMNT: https://drinklmnt.com/perform Renaisance Periodization: https://rpstrength.com/perform Eight Sleep: https://www.eightsleep.com/perform *Timestamps* 00:00:00 Dr. Herman Pontzer 00:01:18 Energy Expenditure & Metabolism 00:03:59 Hunter-Gatherers, Energy Expenditure vs Sedentary Cultures 00:07:19 What is Energy Expenditure?; Maintaining Energy Budget 00:13:42 Sponsors: David Protein & LMNT 00:16:23 Weight Gain; Calories In, Calories Out 00:22:18 Exercise & Calories Burned, Energy Expenditure Changes? 00:29:56 Movement Efficiency, Exercise & Metabolism Research 00:37:55 Metabolic Recalibration & Exercise Threshold 00:43:33 Hunter-Gatherer Groups, Energy Expenditure, Fertility 00:47:23 Sponsors: AG1 & Renaissance Periodization 00:49:53 Pregnancy & Energy; Overtraining, Relative Energy Deficiency Syndrome (REDs) 00:57:37 Metabolism “Slowing Down”, Age or Sex Differences? 01:04:22 Metabolism & Age, Puberty, Older Adults 01:11:51 Body Composition, Individual Food Intake 01:16:49 Sponsor: Eight Sleep 01:18:12 Anthropology, Natural Fallacy, Diversity & Adaptations, Physical Activity 01:27:59 Population, Individual Variation, Diversity, Race 01:34:33 Kidney, eGFR Calculation; Clinical Equations & Race 01:40:51 Genetics, Diversity, Populations; Genetic Testing 01:49:29 One-to-One Gene Fallacy, Height, Environment, Diversity 01:51:20 Height & Weight, Genetics & Environment Interplay 01:56:31 Science Literacy & Research; Diabetes, Heart Disease & Race 02:02:33 Diversity, Physiology & Medicine, EMT 02:07:08 Upcoming Projects, Metabolic Ceilings 02:09:39 Metabolism, Diet & Exercise, Individual Approach 02:14:57 Crash Metabolism?, Herman’s Links 02:17:30 Zero-Cost Support, YouTube, Spotify & Apple Subscribe & Reviews, Sponsors, YouTube Feedback, Social Media, Perform Newsletter #science #health #caloriedeficit #weightloss Disclaimer & Disclosures: https://performpodcast.com/disclaimer-disclosures
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