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Time stamps 0:30 what are ketones The 3 ketone bodies are acetone, acetoacetate and beta hydroxybutyrate Your liver makes ketones from acetyl-CoA 1:02 why does breath smell weird on keto (keto breath) 1:43 what is beta hydroxybutyrate (the best ketone for brain health) 1:55 how are ketones made (ketogenesis) Ketogenesis is the pathway that makes ketones, ketogenesis happens in your liver only Long chain fatty acids are oxidized in the mitochondria to yield acetyl-CoA (beta oxidation) In a ketogenic state / keto metabolic state the acetyl-coa is favourably directed into ketogenesis instead of the tricarboxylic acid / citric acid cycle Under normal conditions (normal carbohydrate diet / fed) the long chain fatty acids are oxidized to acetyl-coa and the acetyl-coa will then enter the tricarboxylic acid / citric acid cycle In starvation states or proper keto diets, if the TCA cycle is slowed or deplete of intermediates then the acetyl-coa enters ketogenesis Ketogenesis should only happen in extreme starvation or on true keto diets 3:13 ketogenic pathway biochemistry Enzymes essential to ketogenesis
 Thiolase, HMG-CoA synthase, HMG-CoA lyase, acetoacetate decarboxylase, betahydroxybutyrate dehydrogenase 4:47 acetoacetate can be cleaved to give CO2, acetone and betahydroxybutyrate 5:37 what is BHB 6:46 how do ketones give you energy (metabolism basics) Acetyl-coa is the common entry point to the tricarboxylic acid / citric acid cycle - glucose, fatty acids and amino acids can all be metabolized into ACoA ACoA can enter the TCA cycle for complete oxidation and to yield large amounts of energy Ketogenesis is when you make ketones from ACoA in the liver, the ketones then enter circulation, travel to the brain where they are converted back into ACoA, now in your brain the ACoA enters the TCA cycle for complete and rapid oxidation thus yielding large amounts of energy 9:02 How to get into ketosis / when are you in ketosis 9:37 what happens when you are starving 10:39 what is keto diet Keto diet macro distribution 5% calories from carbohydrate 25% calories from protein 70% calories from fat 11:12 why is starvation bad for you (protein sparing effect / TCA cycle depletion) 11:59 long term fasting / prolonged fasting diets 13:40 ketosis acidifies your blood and damages organs (ketoacidosis)

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This is the Side B, no vocals, version of this tune. Quite good!

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Welcome back to another Q&A, where Ashleigh and Ben talk about how to optimize your mental and physical wellbeing, considering dieting, workout practices, habits, learning to love discomfort, and more! We begin with a reminder about Ben’s six pillars, and how his workouts are becoming more intellectually focused, a time he takes to be hyper-aware about mobility, stability, skill, and strength. This leads Ben and Ash to hone in on the mental aspects of fitness, and they talk about how working out can be a springboard to creating healthier habits as well as how beneficial mentally arduous training can be for your sense of pride and accomplishment. From there they switch to topics of building muscle on a vegetarian diet, managing stress by controlling carbon dioxide, how to be a great leader by learning to listen, and expanding horizons wherever possible. Next up, Ben weighs in on the question of whether a diet or workout plan should be top of mind if you're aiming to lose fat. We hear the typical process he would take a student through, starting with workouts, and then tweaking calorie intake based on heart rate variability. We look at what habits affect HRV too, and also talk about its connection to sympathetic arousal, considering the fine line between healthy and unhealthy amounts. We end things off hearing about Ben’s love for all his show sponsors, and he shouts out today’s awesome one – Billings Seafood, otherwise known as wildalaskanseafoodbox.com. Head over there and use the code ‘BEN’ and that will get you $20 off your first order and free scallops for life, which is awesome! Timestamps The origins of this podcast and how Ben went from bodybuilding to the six pillars. [0:18] How Ben intellectualizes correct workouts using mobility, stability, skill, and strength. [2:28] Keeping aware of the spine and things that move that shouldn’t during workouts. [6:11] Ben’s two-week workout, workout mindfulness, and becoming consciously competent. [8:50] Using exercise as a way of identifying habits, skills, and attributes you want to create. [14:50] ‘Working in’: mentally arduous workouts and the rush of pushing through what’s uncomfortable. [15:45] Changing your cognitive association with discomfort from negative to positive. [20:58] How to build muscle on a vegetarian/vegan diet taking MAP supplements. [22:33] Controlling stress through breathing and Brian Mackenzie’s webinar. [27:17] Listening and being honest from a place of love: good leadership practices. [28:16] Applying the principle of expanding your horizons to the books you read. [31:39] The importance of curating your thoughts if you want to become a better person. [33:26] Using technology versus a natural process to achieve a desired state. [35:33] How blood flow restriction bands work and how to use them. [37:33] Losing fat by upping workouts before cutting calories/changing diet. [39:51] Using heart rate variability to start pulling calories down once workouts are set. [43:22] The line between healthy and unhealthy states of sympathetic arousal. [44:10] Big issues that could drive HRV down: sleep, breathing, stress, food, training. [45:22] Oura Ring use and getting the best seafood box deliveries from Billings. [46:36] Being calmed by Deadliest Catch and visiting untouched places. [49:38] Thoughts on training heavily in the morning and volume in the evening on the same muscle group. [52:07] --- http://www.mi40nation.com - The worlds best muscle building videos and knowledge to take control of every aspect of your body, check out the MI40Nation: http://www.mi40nation.com http://tinyurl.com/MI40University - click to enroll (FREE) and get a FULL list of ALL the other #MI40University muscle building videos. If you are looking for bodybuilding guidance, videos, workouts, the proper training split to build muscle, see how IFBB PRO Ben Pakulski builds big muscle through the best online program here http://www.mi40nation.com - For Students Of IFBB Pro Ben Pakulski. Where Savvy Men and Women Come To Build Muscle FAST - www.mi40nation.com Don't miss any Ben Pakulski workout or Ben Pakulski training tips by subscribing to the channel: https://www.youtube.com/user/BenPakIFBB And "LIKING" the fanpage here: https://www.facebook.com/IFBBbenpakFANPage

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