Can You Take Semaglutide and Phentermine Together for Weight Loss? Expert Opinions
Chair, Javier Morales, MD, FACP, FACE, Juan Pablo Frías, MD, and Donna H. Ryan, MD, FTOS, discuss T2DM and obesity in this CME activity titled “Is Synergism the Secret to Success? Candid Conversations on Targeting GIP and GLP-1 to Individualize Treatment in Patients With T2DM and Obesity.” For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/KZF865. CME credit will be available until May 7, 2023.
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Obesity is a growing epidemic worldwide, with nearly 40% of adults and 18% of children and adolescents classified as obese. This chronic condition can lead to a myriad of health issues, including heart disease, type 2 diabetes, and certain types of cancer. Despite the availability of various diets, exercise regimens, and weight loss medications, many individuals struggle to achieve sustainable weight loss. However, recent advancements in medical science have shown promise in the form of semaglutide, a medication originally used to treat type 2 diabetes that has shown significant potential in promoting long-term weight loss.
The Science Behind Semaglutide
Semaglutide belongs to a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. These drugs work by mimicking the effects of a naturally occurring hormone in the body that regulates blood sugar levels and satiety. By activating GLP-1 receptors in the brain, semaglutide helps to reduce appetite, increase feelings of fullness, and slow down stomach emptying. In addition to its effects on weight loss, semaglutide has also been shown to improve blood sugar control and reduce the risk of cardiovascular events in patients with type 2 diabetes.
One of the key advantages of semaglutide over other weight loss medications is its long-acting nature. Unlike some drugs that require multiple doses throughout the day, semaglutide is administered once weekly via injection. This convenience not only improves adherence to treatment but also helps to maintain steady levels of the medication in the body, leading to more consistent weight loss results.
Benefits of Long-Term Semaglutide Use
Studies have demonstrated that individuals who use semaglutide for an extended period can achieve significant and sustainable weight loss. In one clinical trial, participants who took semaglutide for 68 weeks lost an average of 15% of their body weight, compared to just 2.4% in the placebo group. This weight loss was maintained over a 5-year follow-up period, highlighting the long-term efficacy of semaglutide in helping individuals achieve and maintain a healthier weight.
In addition to weight loss, long-term use of semaglutide has been associated with improvements in other health markers, such as blood pressure, cholesterol levels, and markers of inflammation. These benefits not only reduce the risk of developing obesity-related comorbidities but also improve overall quality of life for individuals struggling with excess weight.
Potential Side Effects and Considerations
While semaglutide offers significant benefits in terms of weight loss and metabolic health, it is not without potential side effects. Common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. These gastrointestinal symptoms typically improve over time as the body adjusts to the medication. In rare cases, more serious side effects such as pancreatitis or thyroid tumors may occur, so it is important for individuals considering semaglutide for weight loss to discuss the risks and benefits with their healthcare provider.
Another consideration when using semaglutide for long-term weight loss is the cost of the medication. Semaglutide is a prescription medication that may not be covered by all insurance plans, making it inaccessible for some individuals. However, many pharmaceutical companies offer patient assistance programs or discounts to help offset the cost of the medication for those who need it.
Conclusion
In conclusion, the long-term use of semaglutide has shown promise in promoting sustainable weight loss and improving overall health outcomes for individuals struggling with obesity. By harnessing the power of GLP-1 receptors, semaglutide helps to reduce appetite, increase feelings of fullness, and promote steady weight loss over time. While potential side effects and cost considerations should be taken into account, the benefits of semaglutide in terms of weight loss, metabolic health, and quality of life make it a valuable tool in the fight against obesity.
For more information on semaglutide and its use for weight loss, consult with your healthcare provider to determine if this medication is right for you.
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One can't just get a flat tummy just by exercising, fat in the lower waist called tier can not be removed alone fat has to be dissolved all over the body. So it helps a long way in exercising so that you remove the fat all over the body some inches at your waist too. there are certain foods which can definitely increase the metabolism, fat accumulation could be due to various reasons in men and women, it could be thyroid problem, PCOD, lack of exercise and various other underlying causes. Ty to know the cause of you obesity or fat around your waist, lot of studies have shown that taking virgin coconut oil helps in increasing the metabolism and reducing the fat all over your body and your tummy area also. Beetroot extract and pomegranate extract these two things also go a long way. Exercise and the right kind of food are the most important things which will helps you in reducing your fat and get a flat tummy probably.
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Semaglutide, a medication originally approved to treat type 2 diabetes, has recently gained popularity for its off-label use as a weight loss aid. Clinical trials have shown promising results, with participants experiencing significant reductions in body weight compared to placebo groups. However, like any medication, semaglutide is not without its side effects. In this article, we will explore the potential side effects of semaglutide for weight loss and what to watch out for.
1. Gastrointestinal Effects
One of the most common side effects of semaglutide is gastrointestinal distress. This can manifest as nausea, vomiting, diarrhea, or constipation. These symptoms typically occur during the first few weeks of treatment and may improve over time as the body adjusts to the medication. However, if these symptoms persist or become severe, it is important to consult with your healthcare provider.
In rare cases, semaglutide can also cause pancreatitis, an inflammation of the pancreas. Symptoms of pancreatitis include severe abdominal pain, nausea, and vomiting. If you experience these symptoms while taking semaglutide, you should seek immediate medical attention as pancreatitis can be a serious condition that requires medical intervention.
To minimize the risk of gastrointestinal side effects, it is recommended to start with a low dose of semaglutide and gradually increase the dose as tolerated. Additionally, taking the medication with food can help reduce the likelihood of nausea and vomiting.
2. Hypoglycemia
Since semaglutide works by increasing insulin secretion and reducing glucagon production, it can cause hypoglycemia (low blood sugar) in some individuals. Symptoms of hypoglycemia include dizziness, sweating, confusion, and in severe cases, loss of consciousness. It is important for individuals taking semaglutide to monitor their blood sugar levels regularly and be aware of the signs of hypoglycemia.
If you experience symptoms of hypoglycemia while taking semaglutide, it is recommended to consume a fast-acting source of glucose, such as a sugar tablet or juice, to raise your blood sugar levels quickly. Severe cases of hypoglycemia may require medical attention, so it is important to have a plan in place for managing low blood sugar episodes.
Individuals with a history of hypoglycemia or diabetes should exercise caution when taking semaglutide and work closely with their healthcare provider to adjust their diabetes medications as needed to prevent hypoglycemia.
3. Thyroid C-Cell Tumors
Semaglutide has been shown to cause thyroid C-cell tumors in animal studies. While the risk of developing these tumors in humans is low, individuals with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2) should not take semaglutide.
If you experience symptoms such as a lump in the neck, difficulty swallowing, hoarseness, or persistent cough while taking semaglutide, it is important to notify your healthcare provider immediately. These symptoms may indicate a thyroid C-cell tumor, which requires further evaluation and possible treatment.
Regular monitoring of thyroid function and imaging studies may be recommended for individuals at increased risk of developing thyroid C-cell tumors while taking semaglutide. It is important to discuss any concerns or family history of thyroid conditions with your healthcare provider before starting treatment with semaglutide.
4. Injection Site Reactions
As a subcutaneous injection, semaglutide may cause injection site reactions in some individuals. These reactions can include pain, redness, swelling, or itching at the injection site. While these reactions are usually mild and resolve on their own, it is important to rotate injection sites and follow proper injection techniques to minimize discomfort.
If you experience severe or persistent injection site reactions while taking semaglutide, notify your healthcare provider. They may recommend applying a cold pack to the injection site or using a topical corticosteroid ointment to reduce inflammation and discomfort.
Individuals with a history of skin sensitivities or allergies may be at increased risk of developing injection site reactions while taking semaglutide. It is important to discuss any skin concerns with your healthcare provider before starting treatment with semaglutide.
5. Mood Changes
Some individuals may experience mood changes while taking semaglutide for weight loss. This can manifest as anxiety, depression, irritability, or mood swings. These symptoms are typically mild and transient, but if they persist or significantly impact daily functioning, it is important to seek support from a mental health professional.
Individuals with a history of mood disorders or mental health conditions should be monitored closely while taking semaglutide. It is important to discuss any changes in mood or emotional well-being with your healthcare provider to determine the best course of action.
In some cases, adjusting the dose of semaglutide or adding psychotherapy or psychiatric medications may be necessary to manage mood changes effectively. It is crucial to prioritize mental health and well-being while undergoing treatment with semaglutide for weight loss.
Summary
In conclusion, semaglutide can be an effective weight loss aid for many individuals, but it is essential to be aware of the potential side effects and monitor for any warning signs while taking the medication. Gastrointestinal effects, hypoglycemia, thyroid C-cell tumors, injection site reactions, and mood changes are some of the side effects to watch out for while using semaglutide for weight loss. By staying informed, communicating openly with your healthcare provider, and following their guidance, you can safely and effectively incorporate semaglutide into your weight loss journey.
If you have any concerns about the side effects of semaglutide or experience any adverse reactions while taking the medication, do not hesitate to seek medical attention promptly. Your healthcare provider can provide personalized recommendations and support to help you navigate any challenges you may encounter during your weight loss treatment with semaglutide.
Remember, the benefits of achieving a healthy weight and improving your overall well-being can outweigh the potential risks of semaglutide when used appropriately and under the supervision of a healthcare professional. With proper monitoring and proactive communication, you can optimize the benefits of semaglutide for weight loss while minimizing the likelihood of experiencing significant side effects.
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The American Academy of Pediatrics recommends weight-loss drugs for minors in certain instances. A survey from Kaiser Family Foundation found one in eight adults have taken drugs like Ozempic, Wegovy and Mounjaro. As childhood and adolescent obesity cases skyrocket... (CONTINUE READING / SOURCES: https://anthonyblogan.com/big-pharma-wants-to-put-kids-on-weight-loss-drugs-like-ozempic/) ––––––––––––––––––––––– ▶️ UNCLE ABL: https://www.youtube.com/@UncleABL 🌐 WEBSITE: https://www.anthonyblogan.com 🧢 MERCH: http://www.ablmerch.com 📰 NEWS: https://patriotpost.us/ ▶️ RUMBLE: https://rumble.com/c/c-6921350 BITCHUTE: https://www.bitchute.com/channel/ktvdfhdyGBaA/ ––––––––––––––––––––––– 📲 Donate Through PayPal: https://www.paypal.me/ablogan 📲 Donate Through CashApp: $ABL100 📲 Become a Sponsor on Patreon: https://www.patreon.com/anthonyblogan ––––––––––––––––––––––– 🔊 PODCAST: https://podcasters.spotify.com/pod/show/anthony-logan
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Eli Lilly's Phase 3 study highlights the effectiveness of Orforglipron in lowering blood sugar and promoting weight loss, potentially offering a convenient alternative to GLP-1 injections.
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