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In this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Jens Juul Holst, a renowned Danish physician and physiologist, to discuss GLP-1, a hormone transforming our understanding of metabolic health. Dr. Holst, who discovered and described GLP-1, explains its role as a gut-derived hormone that regulates appetite, insulin secretion, and digestion, offering a groundbreaking approach to managing obesity and type 2 diabetes. The conversation explores how GLP-1 receptor agonists, have evolved into powerful medications. These drugs help patients achieve significant weight loss, reverse diabetes, improve cardiovascular health, reduce inflammation, and potentially enhance cognitive function. Dr. Holst delves into their long-term implications for preventing diabetes, extending health spans, and even reducing the risks of obesity-related cancers and improving fertility. Dr. Holst emphasizes that while GLP-1 offers life-changing benefits, sustainable health still hinges on balanced diets and regular physical activity. This episode provides a fascinating look at the intersection of science, medicine, and lifestyle in promoting longevity. Sign up for updates about each new episode: https://info.insidetracker.com/longevitybydesign View show notes here: https://blog.insidetracker.com/longevity-by-design-podcast-jens-juul-holst Episode highlights: Introduction: 00:00:00 What is GLP-1: 00:03:00 what is a GLP-1 agonist: 00:04:15 what are the target organs of the GLP-1 agonist?: 00:06:30 what is the effect of the GLP-1 agonist on a diabetic patient? : 00:10:00 What percentage of a diabetic patient on GLP-1 have complete remission: 00:11:30 How long did it take to bring a drug to market from the moment you first discovered it: 00:23:30 What is the GLP-1 effect on cognition and dementia: 00:29:00 GLP-1 effect on kidney diseases: 00:32:00 GLP-1 positive effect on fertility: 00:35:00 GLP-1 positive effect on cancer: 00:37:30 Should a patient be on GLP-1 for life: 00:41:00 GLP-1 related side effects: 00:48:00 GLP-1 effect on resting heart rate: 00:52:30 GLP-1 related side effects: 00:48:00 GLP-1 from Lilly vs novo nordisk: 00:55:00 GLP-1 oral versus the injectable: 00:58:00 GLP-1 effect on lifespan: 01:00:30 GLP-1 effect on lifespan: 01:00:30 What led you to become a scientist: 01:03:00 The story of discovering the GLP-1: 01:04:30 How did you successfully extend the half-life of the GLP-1 agonist: 01:09:00 GLP-1 moving from once a day to once a week: 01:16:00 Top tip to improve healthspan: 01:18:00 GLP-1 Agonists: A Game-Changer for Diabetes and Obesity Dr. Jens Juul Holst explores the revolutionary impact of GLP-1 agonists in treating diabetes and obesity. These medications mimic a natural gut hormone to regulate insulin secretion, appetite, and weight. Through their ability to normalize blood glucose levels and promote significant weight loss, GLP-1 agonists have transformed the lives of patients with type 2 diabetes and obesity. Holst highlights their success in enabling over 50% of diabetes patients to achieve normal glucose levels while addressing the systemic health risks tied to obesity. This innovation represents a monumental leap in metabolic disease management. Beyond Weight Loss: Cardiovascular and Inflammatory Benefits of GLP-1 Dr. Holst emphasizes the additional health advantages of GLP-1 agonists, beyond their effects on diabetes and obesity. These drugs improve cardiovascular outcomes by reducing major adverse events such as heart attacks and strokes. They also decrease systemic inflammation, a common issue in metabolic diseases. Holst points out that GLP-1 therapy’s dual action on vascular health and inflammation positions it as a comprehensive solution for improving long-term health outcomes in patients with diabetes or obesity. The Impact of GLP-1 on Fertility Dr. Holst explores GLP-1’s surprising potential in fertility treatments, particularly for individuals with metabolic-related infertility issues, such as polycystic ovary syndrome (PCOS). He explains that improving metabolism and reducing insulin resistance with GLP-1 therapy can enhance fertility outcomes for both men and women. Although he urges caution due to limited long-term data, Holst notes the promising effects observed in clinical experiences. “If you can ameliorate the metabolism of these individuals, they will immediately become pregnant. And we knew that already. You can even do it with metformin…Once GLP-1s were introduced, it turned out that yes, these people became pregnant.” We Appreciate You! As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: https://info.insidetracker.com/podcast For science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
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Welcome to Gold Coast Keto.com, the ultimate destination for all things ketogenic! Whether you’re a seasoned keto pro looking for new recipes and resources or a beginner just starting your keto journey, Gold Coast Keto.com has everything you need to succeed. Our website is dedicated to providing you with the tools, information, and inspiration to help you achieve your health and wellness goals through the ketogenic lifestyle. From delicious recipes to informative articles, we’ve got you covered every step of the way.
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The ketogenic diet has gained popularity in recent years for its numerous health benefits. By drastically reducing your carbohydrate intake and increasing your consumption of healthy fats, your body enters a state of ketosis where it burns fat for fuel instead of glucose. This can lead to weight loss, improved energy levels, better mental clarity, and even reduced risk of chronic diseases like diabetes and heart disease.
One of the primary benefits of the ketogenic diet is its ability to help you lose weight and keep it off. By reducing your intake of carbohydrates and sugar, your body switches from burning glucose for energy to burning fat instead. This can lead to rapid weight loss, particularly in the form of stubborn belly fat. Many people find that they can achieve their weight loss goals more easily and sustainably on a ketogenic diet compared to traditional low-fat diets.
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Our recipes are designed to be easy to follow, using simple ingredients that you can find at your local grocery store. We provide detailed instructions and tips to help you prepare delicious meals that are not only keto-friendly but also family-friendly. Whether you’re in the mood for a creamy keto Alfredo pasta, a savory bacon-wrapped chicken, or a decadent chocolate avocado mousse, we have something for everyone to enjoy.
In addition to our collection of recipes, we also offer helpful resources and guides to help you navigate the world of keto cooking with confidence. From meal planning and grocery shopping tips to cooking techniques and kitchen tools, we’re here to support you every step of the way on your culinary journey. Let us help you discover the joy of cooking and eating delicious, healthy food that nourishes your body and soul.
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Embarking on a ketogenic lifestyle can be a daunting prospect, especially if you’re new to the diet. That’s why Gold Coast Keto.com is here to provide you with expert advice and support to help you achieve success on your keto journey. Our team of experienced keto enthusiasts and health professionals are here to answer your questions, provide guidance, and offer encouragement every step of the way.
Whether you’re looking for personalized meal plans, fitness recommendations, or tips for overcoming common challenges on a ketogenic diet, we’ve got you covered. Our experts can help you navigate the ins and outs of keto living so that you can achieve your health and wellness goals with confidence. We believe that everyone deserves to experience the life-changing benefits of the ketogenic diet, and we’re here to help you every step of the way.
In addition to our expert advice, we also offer a supportive community where you can connect with like-minded individuals who are also following a ketogenic lifestyle. Our online forums, social media groups, and virtual events provide a platform for you to share your experiences, ask questions, and find inspiration from others who are on a similar journey. Join us on Gold Coast Keto.com and become a part of our thriving community of keto enthusiasts who are dedicated to helping each other succeed.
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At Gold Coast Keto.com, we know that having access to high-quality keto products is essential for your success on the ketogenic diet. That’s why we’ve curated a selection of premium keto-friendly products to help you stay on track and achieve your health and wellness goals. From pantry staples to snacks and supplements, we’ve got everything you need to support your keto lifestyle in one convenient place.
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In conclusion, Gold Coast Keto.com is your go-to destination for all things ketogenic, offering a wealth of resources, recipes, advice, and products to help you succeed on your keto journey. Whether you’re a seasoned keto veteran or a newbie just starting out, we’re here to support you every step of the way. Join us on Gold Coast Keto.com and discover the joy of living a healthy, delicious, and fulfilling ketogenic lifestyle.
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Semaglutide, a medication used to treat type 2 diabetes, has recently gained popularity for its potential to aid in weight loss. Clinical trials have shown that different doses of semaglutide can lead to significant weight loss in individuals struggling with obesity. With obesity becoming a growing concern worldwide and the limited options available for effective weight management, the use of semaglutide holds promise for many. This article will explore the different semaglutide doses that have been found to be effective for weight loss, shedding light on this emerging treatment option.
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Semaglutide belongs to a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. These medications work by mimicking the effects of a hormone called GLP-1, which is normally released in response to food intake. GLP-1 helps regulate blood sugar levels and appetite, making it a potential target for weight management. Studies have shown that semaglutide can reduce appetite, increase feelings of fullness, and ultimately lead to weight loss in individuals with obesity.
One of the key benefits of semaglutide is its ability to target multiple factors that contribute to weight gain. In addition to reducing appetite and increasing feelings of fullness, semaglutide can also improve insulin sensitivity and promote the breakdown of fat in the body. This multifaceted approach sets semaglutide apart from other weight loss medications, making it a promising option for individuals struggling to lose weight.
Another advantage of semaglutide is its convenience as a once-weekly injection. This dosing schedule makes it easier for individuals to adhere to their treatment regimen compared to medications that require multiple daily doses. Additionally, the long-acting nature of semaglutide allows for more consistent blood levels of the medication, potentially enhancing its effectiveness for weight loss.
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Several clinical trials have evaluated different doses of semaglutide for weight loss in individuals with obesity. The most commonly studied doses include 0.5 mg, 1.0 mg, and 2.4 mg. These doses have been compared to a placebo or other weight loss medications to assess their efficacy and safety.
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The popularity of the ketogenic diet has led to the creation of various keto-friendly products, including FDA-approved keto gummies. These gummies offer a convenient and delicious way to enjoy the benefits of the keto diet without having to prepare complicated meals or count macros. In this comprehensive guide, we will explore the benefits of FDA-approved keto gummies and how they can support your ketogenic lifestyle.
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FDA-approved keto gummies are made with high-quality ingredients that are specifically chosen to support a ketogenic diet. These gummies are low in carbs and sugar, making them a suitable option for those following a keto lifestyle. Additionally, they are often enriched with essential nutrients such as vitamins and minerals to ensure you are getting the necessary nutrients while on a keto diet.
One of the key benefits of FDA-approved keto gummies is their convenience. They are easy to carry around and can be consumed on the go, making them a convenient option for busy individuals. Moreover, they are available in a variety of flavors, making them a tasty alternative to traditional keto-friendly snacks.
Another benefit of FDA-approved keto gummies is that they can help curb sugar cravings. The low-carb and sugar content of these gummies can satisfy your sweet tooth without causing a spike in blood sugar levels. This can make it easier to stick to your keto diet and avoid unnecessary cheat days.
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When looking for FDA-approved keto gummies, it is essential to read the label carefully. Make sure the gummies are low in carbs and sugar, as these are the key criteria for a keto-friendly product. Additionally, look for gummies that are enriched with vitamins and minerals to ensure you are getting essential nutrients while on a keto diet.
It is also important to choose FDA-approved keto gummies from reputable brands. Look for companies that follow strict manufacturing standards and prioritize quality control. You can also check for customer reviews to see what others have to say about the product.
Consider the flavor options when choosing keto gummies. Some brands offer a wide range of flavors, while others may have limited options. Choose a flavor that you enjoy to make it easier to incorporate the gummies into your daily routine.
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There are several ways you can incorporate FDA-approved keto gummies into your diet. You can enjoy them as a snack between meals, or as a dessert after a keto-friendly meal. They can also be used as a pre-workout energy boost or a post-workout recovery snack.
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Experiment with different ways to incorporate keto gummies into your diet to find what works best for you. Whether you enjoy them on their own or use them in recipes, FDA-approved keto gummies can be a tasty and convenient addition to your ketogenic lifestyle.
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1. Are FDA-approved keto gummies safe to consume?
Yes, FDA-approved keto gummies are considered safe for consumption. They are made with high-quality ingredients and undergo rigorous testing to ensure they meet FDA standards.
2. Can I eat keto gummies on a non-keto diet?
While keto gummies are specifically designed for those following a ketogenic diet, you can still enjoy them as a low-carb snack even if you are not on a keto diet.
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