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Antag launches a Phase Ia trial for GIPR-targeting drug AT-7687, exploring combination potential with GLP-1s. Korea United Pharm eyes semaglutide biosimilars and expands facilities. At AMCP 2025, Prime Therapeutics shares real-world GLP-1 data, winning “Article of the Year.” Five scientists behind Ozempic and Wegovy receive the $3M Breakthrough Prize. Eli Lilly sues compounders of tirzepatide amid resolved shortages and price cuts. CMS excludes anti-obesity drugs from 2026 Medicare coverage, raising concerns over access for seniors and causing stock dips for Lilly and Novo Nordisk.

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Full interview: http://sigmanutrition.com/episode65/ Episode 65: Lyle McDonald is on the show to discuss the metabolic adaptations that take place when dieting, the connection between cortisol and water retention and the role of leptin in dieting and weight regain. In this episode we discuss: Metabolic adaptations to dieting Low calories + lots of cardio = no weight loss??? What’s actually going on The connection between cortisol and water retention The central role of leptin in bodyweight regulation Leptin resistance Effects of lowered calories on leptin Gender differences in hormonal responses to dieting Carbohydrate refeeds: Can they mitigate leptin drops? Which of Lyle’s books should YOU read?

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Introduction Losing body fat quickly requires a combination of smart dietary choices, consistent physical activity, and healthy lifestyle habits. While sustainable fat loss is a long-term process, certain strategies can help accelerate the process safely and effectively. Here are five proven ways to lose body fat fast. 5 Ways to Lose Body Fat Fast. 1. Adopt a High-Protein, Low-Carb Diet Reducing carbohydrate intake while increasing protein consumption can help you burn fat by boosting metabolism and curbing hunger. Foods like lean meats, eggs, and legumes not only promote fat loss but also help retain muscle mass. 2. Incorporate High-Intensity Interval Training (HIIT) HIIT workouts alternate between intense bursts of activity and short recovery periods, maximizing calorie burn in a short time. Studies show that HIIT is highly effective for fat loss, especially in the abdominal area. 3. Stay in a Calorie Deficit To lose fat, you need to consume fewer calories than you burn. Use apps or calculators to track your daily caloric intake, ensuring it aligns with your fat loss goals. Combine this with regular exercise for the best results. 4. Prioritize Strength Training Lifting weights or engaging in bodyweight exercises helps build lean muscle mass, which increases your resting metabolic rate. The more muscle you have, the more calories you burn, even at rest. 5. Improve Sleep and Manage Stress Lack of sleep and high stress levels can lead to hormonal imbalances, including increased cortisol, which promotes fat storage. Aim for 7-8 hours of quality sleep and practice stress-reducing activities like meditation or yoga. Conclusion While losing body fat quickly is possible, it’s important to prioritize sustainable and healthy practices. A balanced approach that combines a proper diet, regular exercise, and healthy lifestyle choices will yield the best results over time. Remember, consistency is key to achieving and maintaining your fat loss goals. Thanks For watching . #fat #fatloss #weight #weightloss #executive #art #artistic #focus #goals #goalsetting #consistency #focus #consistent #real #decent #confidence #confidenceboost #thecent #lifestyle #oldmoney #sigma #fitness #menlifestyle #motivation #gentlmen #gentleman #overconfidence #motivational #motivation #motivationalvideo #motivationalquotes #thecent #lie #scam #executive #art #artistic #focus #goals #goalsetting #consistency #focus #consistent #confidence #confidenceboost #selfconfidence #fitness #lifestyle #thecent #fit #body #sixpack #abs #mensfitness #bodyfat #facefat #goodfat #badfat #diet #exercise #calories #cardio #weighttraining #weightlifiting #real #decent #confidence #lifestyle #sigma #fitness #motivation #gentleman #overconfidence #motivational #motivation #lie #scam #executive #art #artistic #focus #goals #consistency #focus #consistent #change #fat #fastfatloss #proven #fitnessmotivation #facts #fatlossjourney #fatlosstips #leanbody #cardio #fatlosssecrets

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http://bit.ly/flattummy - Get the full video at Truth About 6 Pack Abs - The #1 Rated Abs Program on the Internet In this FREE presentation below, you'll find: -Shocking foods that burn belly fat -2 so-called "health" foods that you should NEVER eat (they can actually increase stomach fat) -Motivation secrets for lifelong fitness success -1 unique "trick" to reduce junk-food cravings -Weird workouts that burn abdominal fat faster than typical "cardio" -The TRUTH about getting flat abs without bogus "fat burner" pills The Hidden Dangers of Your Excess Abdominal Fat - It's More Serious Than a Vanity Issue! by Mike Geary, Certified Nutrition Specialist, Certified Personal Trainer Did you know that the vast majority of people in this day and age have excess abdominal fat? The first thing that most people think of is that their extra abdominal fat is simply ugly, is covering up their abs from being visible, and makes them self conscious about showing off their body. However, what most people don't realize is that excess abdominal fat in particular, is not only ugly, but is also a dangerous risk factor to your health. Scientific research has clearly demonstrated that although it is unhealthy in general to have excess body fat throughout your body, it is also particularly dangerous to have excess abdominal fat. There are two types of fat that you have in your abdominal area. The first type that covers up your abs from being visible is called subcutaneous fat and lies directly beneath the skin and on top of the abdominal muscles. The second type of fat that you have in your abdominal area is called visceral fat, and that lies deeper in the abdomen beneath your muscle and surrounding your organs. Visceral fat also plays a role in giving certain men that "beer belly" appearance where their abdomen protrudes excessively but at the same time, also feels sort of hard if you push on it. Both subcutaneous fat and visceral fat in the abdominal area are serious health risk factors, but science has shown that having excessive visceral fat is even more dangerous than subcutaneous fat. Both of them greatly increase the risk your risk of developing heart disease, diabetes, high blood pressure, stroke, sleep apnea, various forms of cancer, and other degenerative diseases. Part of the reason visceral fat is particularly dangerous is that it apparently releases more inflammatory molecules into your body on a consistent basis. If you care about the quality of your life and your loved ones, reducing your abdominal fat should be one of your TOP priorities! There's just no way around it. Besides, a side-effect of finally getting rid of all of that excessive ugly abdominal fat is that your stomach will flatten out, and if you lose enough stomach fat, you will be able to visibly see those sexy six pack abs that everyone wants. So what gets rid of extra abdominal fat? Is there actually a REAL solution beyond all of the gimmicks and hype that you see in ads and on commercials for "miracle" fat loss products? The first thing you must understand is that there is absolutely NO quick fix solution. There are no pills or supplements of any sort that will help you lose your abdominal fat faster. Also, none of the gimmicky ab rockers, rollers, or ab belts will help get rid of abdominal fat either. You can't spot reduce your stomach fat by using any of these worthless contraptions. It simply doesn't work that way. The ONLY solution to consistently lose your abdominal fat and keep it off for good is to combine a sound nutritious diet full of unprocessed natural foods with a properly designed strategic exercise program that stimulates the necessary hormonal and metabolic response within your body. Both your food intake as well as your training program are important if you are to get this right. I've actually even seen a particular study that divided thousands of participants into a diet-only group and an exercise/diet group. While both groups in this study made good progress, the diet-only group lost significantly LESS abdominal fat than the diet & exercise combined group. For more info check out ... http://bit.ly/flattummy

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