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In this power-packed episode, we explore the game-changing science behind GLP-1 agonists—the revolutionary drugs transforming treatment for type 2 diabetes and obesity. Discover how decades of research, from hormone discovery to drug innovation, led to today’s best-selling medications like Ozempic, Wegovy, and Rybelsus. But that’s not all—this episode also dives into the digital world with an overview of StoneFly, Inc.’s cutting-edge data storage and disaster recovery solutions. Learn how robust IT infrastructure is helping protect sensitive health data and power next-gen biotech. 🔬 Whether you're interested in pharmaceutical innovation, healthcare tech, or secure data systems, this episode delivers insight, inspiration, and actionable takeaways.

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Click Here to Subscribe: http://Bit.ly/ThomasVid Get Grass-Finished Meat Delivered to Your Doorstep with Butcher Box: https://butcherbox.pxf.io/c/1434763/1577973/16419 Website: http://ThomasDeLauer.com The 4 Week Keto Diet - How to Cut on Keto - Thomas DeLauer Resistance Training Meta Analysis - Nutrients Looked to see if resistance training prevents muscle loss induced by caloric restriction The review randomized clinical trials (RCT) comparing the effects of CR with (CRRT) or without RT on lean body mass (LBM), fat body mass (FBM), and total body mass (BM) The six RCTs included in the review applied RT three times per week, for 12 to 24 weeks, and most CR interventions followed diets of 55% carbohydrate, 15% protein, and 30% fat RT reduced 93.5% of CR-induced LBM loss (0.819 kg [0.364 to 1.273]), with similar reduction in FBM and BM, compared with CR Concluded that CRRT is able to prevent almost 100% of CR-induced muscle loss, while resulting in FBM and BM reductions that do not significantly differ from CR. Despite losing weight, resistance training still tears the actin and myosin, forcing the body to repair them, building them back up https://www.ncbi.nlm.nih.gov/pubmed/29596307 Fasted Training Fasting & Hormone Sensitive Lipase Exercising in a fasted state increases both lipolysis and fat oxidation rates - Your body's fat burning processes are controlled by your sympathetic nervous system and your SNS is activated by exercise and lack of food When you train with your insulin at a baseline level, your body is able to both mobilize and burn more fat during your workouts than when insulin levels are elevated The combination of fasting and exercising maximizes the impact of cellular factors and catalysts (cyclic AMP and AMP Kinases), which force the breakdown of fat and glycogen for energy Study - The Journal of Physiology: Exercise in the fasted state facilitates fibre type-specific intramyocellular lipid breakdown and stimulates glycogen resynthesis in humans https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1464435/ Study from the European Journal of Applied Physiology Subjects were split into two groups that were trained on two occasions separated by three weeks - one of the sessions was performed on an empty stomach after an overnight fast Found: Increased p70s6k phosphorylation during intake of a protein–carb drink following resistance exercise in the fasted state - fasted training group saw a bigger increase in p70s6k p70s6 kinase serves as an indicator of muscle growth https://link.springer.com/article/10.1007%2Fs00421-009-1289-x Supplements DIM DIM is a naturally occurring byproduct of indole-3-carbinol (IC3), and IC3 helps the liver to metabolize estrogen more efficiently via upregulating the CYP1A2 enzyme (CYP1A2 is an enzyme that helps to break down toxins in our bodies) It also simultaneously converts strong estrogen molecules into less potent ones (via downregulation of the CYPB1B enzyme and upregulation of CYP1A2 enzyme) - results in reduced estrogen levels and a more favorable estradiol/estrone ratio Fish Oil (Muscle Growth & Fat Loss) Muscle Growth A study published in the journal Clinical Science looked at 9 healthy participants, age 25-45, who led a sedentary lifestyle that supplemented with 4 grams of DHA and EPA daily for an 8-week period The pathways which regulate protein synthesis (mTORSer2448 and p70s6kThr389) increased by roughly 50% (50% more active in the presence of higher omega-3 fatty acid levels) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499967/ Fat Loss Study 1 - Satiation A study published in the journal Appetite looked at the effects of omega 3’s on appetite- was assessed in humans taking part in calorie restricted weight loss diets. Participants were given 1 of 4 diets including no seafood, lean fish 3 times a week, fatty fish 3 times a week and omega 3 capsules (6 a day) Scientists found that those who consumed meals high in omega 3’s felt more full directly after and 2 hours after Omega 3’s modulated hunger signals that control hunger and fullness in the body, which can help you eat less and lose weight - specifically modulated postprandial satiety https://www.ncbi.nlm.nih.gov/pubmed/18602429 Study 2 - Brown Fat & White Fat A Japanese study published in Scientific Reports fed two groups of mice a high-fat diet - one group, however, also consumed fish oil The latter group gained significantly less weight and fat, and had a hotter core temperature, due to an increase in brown fat https://www.nature.com/articles/srep18013 Magnesium Magnesium directly interacts with your muscle tissue through a process called ion transportation It bonds with specific receptor sites that open up the cell membrane and allow other mineral ions to enter, such as calcium and potassium - these ions help regulate muscle contractions and might ease muscle tension

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Watch ►Healthy Weight Loss | Dr.Vineela Diet Plan | Weight Loss Diet | #shorts #sumantv #SumanTVHealth For More Latest Health and Beauty Tips, Tips to control Diabetes stay Tuned to Sumantv Health and Subscribe: https://goo.gl/ersom6 DISCLAIMER: The information provided on this channel and its videos is for general purposes only and should not be considered as professional advice. We are trying to provide a perfect, valid, specific, detailed information .we are not a licensed professional so make sure with your professional consultant in case you need. All the content published in our channel is our own creativity

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In this video, Dr. Doug Lucas discusses the impact of GLP-1 drugs, such as semaglutide and tirzepatide, on bone health. He reviews various studies, both animal and human, to assess how these drugs affect bone turnover markers and overall bone health. Dr. Doug emphasizes the need for more research to understand the long-term effects of these medications and shares insights from his clinical experience with patients using these drugs. He concludes by stressing the importance of a holistic approach to bone health, rather than relying solely on medication. *STUDIES* https://pubmed.ncbi.nlm.nih.gov/31967113/ https://www.semanticscholar.org/paper/Chronic-administration-of-Glucagon-like-peptide-1-Pereira-Jeyabalan/53ed188a6ec91cc391e1f51f0b88677f6846a45b?utm_source=consensus https://www.semanticscholar.org/paper/A-Pilot-Study-Showing-Acute-Inhibitory-Effect-of-on-Nissen-Marstrand/35d921df93a9401d4cb94a8435c8a10383c7f4a0?utm_source=consensus https://www.semanticscholar.org/paper/GLP-1-Receptor-Agonist-Treatment-Increases-Bone-and-Iepsen-Lundgren/a73891c7cdf9a91976a78d61cbf4efdc410e8cdf?utm_source=consensus https://www.semanticscholar.org/paper/Separate-and-Combined-Effects-of-GIP-and-GLP-1-on-Bergmann-Lund/e118cf9b0a74dd9c461f0fc94447a4c60fdc0eaf?utm_source=consensus https://www.semanticscholar.org/paper/Effects-of-Glucagon-Like-Peptide-1-Receptor-Agonist-Kim-Choi/4aeb6dd5628cfce20f64fd39b82b3276ca9e02dd?utm_source=consensus 🩺⚡️ *INTERESTED IN OUR OPTIMAL BONE HEALTH PROGRAM?* Click the link below to speak with a team member! Click here: https://www.optimalhumanhealth.com/membership 🦴⚡️ *SIGN UP FOR MY FREE MASTERCLASS USING THE LINK BELOW!* Click here: https://www.optimalhumanhealth.com/build-bone Masterclass details: Hosted by Doug Lucas, DO, Board Certified Orthopedic Surgeon and Anti-Aging Specialist, you'll gain insight into the lifestyle, nutrition, testing, and medical solutions for Osteoporosis management and yes, possibly, even reversal. 💻⚡️ *OSTEOCOLLECTIVE:* https://www.optimalhumanhealth.com/osteocollective 📖 ⚡️*Get my book "The Osteoporosis BreakThrough"* https://bit.ly/OsteoporosisBreakthrough I would be grateful if you could consider sharing your thoughts by leaving a review once you've had a chance to read it. Your feedback can inspire others on their own path to bone health excellence. https://bit.ly/LeaveABookReveiw 💻⚡️ *FOR MORE RESOURCES* https://www.drdouglucas.com ▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️ This channel is focused on Bones, Hormones, and Healthspan to help midlife women and beyond aim for optimal, not average, and reignite their spark! The videos on this channel will be focused around helping women navigate healthspan and longevity through the lens of osteoporosis, perimenopause, and menopause. When it comes to osteoporosis and menopause providers and educators often get tunnel vision and your symptoms might get better, but if you don't keep longevity in mind, symptom improvement may come at the expense of heart and brain health. Subscribe and follow along as Dr. Doug Lucas explores the research and clinical applications surrounding women's health. *ABOUT DR. DOUG LUCAS* Dr. Doug Lucas: Owner/founder of Optimal Bone Health and Optimal Human Health. My team and I work together to create custom bone optimization plans for individuals based around supplements, hormone optimization, peptides and more in order to increase bone health and longevity! Optimal Bone Health: https://www.optimalhumanhealth.com/ Instagram: https://www.instagram.com/dr_douglucas/ Facebook: https://www.facebook.com/DrDougLucas/ Linkedin: https://www.linkedin.com/in/doug-lucas-b0243522/ #osteoporosis #exercise #healthspan *Watch and Enjoy! Dr. Doug Lucas Key Moments in this Episode* ========================= Chapters 00:00 Introduction to GLP-1 Drugs and Bone Health 07:53 Research Findings on GLP-1 Drugs and Bone Turnover 12:39 Clinical Experience and Future Directions

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On the other hand, the kids too are getting more inclined in watching cartoons and playing video and online computer games thus resulting lower physical activities among them as well. For more information please visit following official site : http://americaferreraweightloss.net/

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If you work out in the morning everyday then you're one of the few people who start their day right. That's because morning exercise boosts your metabolism and improves circulation - giving you energy for the whole day, while also getting you in shape and fit. Today's total body workout is designed to work all the major muscle groups in your body and it must be done every morning, for at least 3 to 4 weeks. This is the way to give your day a jumpstart, burn calories and get fit in just 11 minutes a day! Make sure to subscribe to Roberta's Gym channel if you want to receive new video workouts like this one regularly everyday, Monday to Friday. Good luck and let's begin our morning workout routine!💪❤️