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Register for this webinar: https://xtalks.com/webinars/sarcopenia-changes-and-challenges-in-body-composition-with-glp-1-receptor-agonist-based-weight-loss-therapies/?utm_source=youtube&utm_medium=videopromo&utm_campaign=24q242 Recent trials of GLP-1 receptor agonist-based therapies using weight loss primary endpoints have shown remarkable efficacy that approaches that of bariatric surgery (~20–25 percent compared to 25–30 percent with bariatric surgery). GLP-1 receptor agonist-based therapies have also shown compelling benefits on other obesity comorbidities such as glycaemic control in type 2 diabetes, cardiovascular disease risk, progression of chronic kidney disease, obstructive sleep apnea and metabolic-dysfunction associated steatotic liver disease. Although changes in fat distribution from GLP-1 receptor agonist-based therapies are key to understanding many of the health outcome benefits, the impact of skeletal muscle loss on long-term health outcomes remains to be clarified. While skeletal muscle loss is not specific to GLP-1 receptor agonist-based therapies, the degree of weight loss compared to other anti-obesity medications (AOMs) has exposed the limitations of using weight change as a primary endpoint in clinical trials and has highlighted the need for including accurate measurements of changes in muscle mass and function in AOM clinical trials. The evolving requirement for accurate assessment of body composition (BC) in clinical trials is further driven by: - The variability of changes in fat loss and BC changes to different GLP-1 receptor agonist-based therapies - The variable changes in BC of diverse ethnic and racial populations in response to GLP-1 receptor agonist-based therapies - The expansion of treatment populations by GLP-1 receptor agonist-based therapies to include adolescents with obesity - The development of new therapies aimed at preserving muscle mass and function - Understanding changes in regional adiposity such as pathogenic visceral adipose tissue, liver adipose tissue and epicardial adipose tissue In this webinar, the speakers will review recent clinical trial data that represents the current state of scientific knowledge and evaluate the impact of the data on loss of muscle mass following GLP-1 receptor agonist-based therapies and the need for accurate and tailored assessments of BC in clinical trials. Register for this webinar today to delve into the latest clinical trial data on GLP-1 receptor agonist-based therapies and their impact on weight loss and body composition. Register for this webinar: https://xtalks.com/webinars/sarcopenia-changes-and-challenges-in-body-composition-with-glp-1-receptor-agonist-based-weight-loss-therapies/?utm_source=youtube&utm_medium=videopromo&utm_campaign=24q242 #Obesity #DrugDevelopment #ClinicalResearch #ClinicalData #TherapeuticAreas #WeightLoss #BodyComposition #FattyLiver #Sarcopenia #GLP1Agonist #GLP1Agonists #GLP1Drugs

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"Metformin: The Weight Loss Wonder Drug?" Description: If you're struggling to lose weight, you might have heard about Metformin. Originally developed to treat type 2 diabetes, Metformin has gained popularity as a weight loss aid in recent years. But does it really work? In this video, we'll take a deep dive into Metformin and its effects on weight loss. We'll start by explaining how Metformin works and what it does to your body. We'll also explore the research behind Metformin as a weight loss drug, and what the science says about its effectiveness. We'll discuss the potential side effects of taking Metformin, as well as who should and shouldn't take the drug. We'll also go over some of the other health benefits of Metformin beyond weight loss, such as its ability to lower blood sugar levels and improve insulin sensitivity. Throughout the video, we'll provide practical tips and advice for those considering taking Metformin for weight loss, including how to talk to your doctor and what to expect when starting the medication. By the end of this video, you'll have a better understanding of what Metformin is, how it works, and whether it's a viable weight loss option for you. So if you're curious about Metformin and its potential as a weight loss drug, be sure to tune in! #metformin #diabetes #type2diabetes #insulinresistance #health #medicine #treatment #glucose #lifestylechanges #bloodsugar #PCOS #weightloss #healthyhabits #doctor #healthylifestyle #pharmacy #wellness #fitness #nutrition #wellbeing #selfcare #healthcare #chronicdisease #hormonalimbalance #insulin #metabolism #prescription #drug #endocrinology #healtheducation #healthydiet #medication #sugarcontrol #wellnessjourney #balanceddiet #healthtips #healthyliving #weightmanagement #healthandwellness #healthadvice #wellnesscoach #fitnessmotivation #healthysnacks #healthiswealth #medicinesafety #dosage #druginteractions #healthyrecipes #nutritionist #healthylifestyletips #healthblog #healthandfitness #healthylivingtips #metforminsideeffects #bloodsugarcontrol #hypoglycemia #diabetesmanagement #healthylifestylechoices #healthylifestylehabits #fitnessgoals #bloodglucose #healthcaretips #metforminweightloss #medicinecabinet #healthcoach #healthyhabitsforlife #insulinmanagement #healthychoices #healthandwellnesscoach #metformintherapy #healthfacts #healthandnutrition #healthylivinghabits #medicinehat #diabetesawareness #healthyeating #healthyeatinghabits #healthandfitnessjourney #lifestylemedicine #pharmacist #healthbenefits #fitnessinspiration #healthyfood #healthyeatingtips #bloodsugarlevels #healthytips #healthpromotion #healthylifestylemovement #holistichealth #medicineball #healthbloggers #healthylivingjourney #healthybody #healthylifestyleblogger #healthyfoodideas #healthylivingtipsandtricks #healthinspiration #healthysnackideas #healthandwellnessblog #healthylivingchallenge What is the main side effect of metformin? Metformin is an oral medication used to treat type 2 diabetes that is generally well tolerated. GI upset, especially diarrhea, is the most common side effect. This typically decreases over time. Although rare, lactic acidosis, hypoglycemia, and vitamin B12 deficiency can occur What is Glucophage? Glucophage is an oral diabetes medicine that helps control blood sugar levels. Glucophage is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. What is Glucophage used for? Treatment of type 2 diabetes mellitus, particularly in overweight patients, when dietary management and exercise alone does not result in adequate glycaemic control. In adults, Glucophage may be used as monotherapy or in combination with other oral antidiabetic agents or with insulin. What are the benefits of taking Glucophage? Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems