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Are GLP-1 weight loss drugs the solution we've been waiting for—or just another manifestation of diet culture in disguise? In this episode 42, "GLP-1 Medications Explained: What You Need to Know in 2025," of the How to Fitness Podcast, we dive into the hype, hope, and hard truths surrounding medications like Ozempic and Wegovy. Join us as we break down the science behind GLP-1 drugs, discuss their benefits for obesity and metabolic health, and explore the potential risks and ethical dilemmas tied to their use. From celebrity endorsements to compounding pharmacies and societal pressures, this episode uncovers the complexities of these groundbreaking yet polarizing treatments. Tune in to get the facts, hear real-world insights, and learn how to navigate this evolving topic with clarity. TIMESTAMPS: 00:00 Introduction and Personal Opinions on Weight Loss Medications 00:23 Welcome to the How to Fitness Podcast 01:07 Revisiting the Ozempic Revolution 03:04 Understanding GLP-1 Medications 04:19 Mechanisms and Effects of Semaglutide 07:00 Personal Experiences and Observations 10:22 The Broader Impact and Misconceptions 20:34 Celebrity Influence and Public Perception 23:16 Exploring Telehealth and Accessibility 23:57 Exploring Telehealth Weight Loss Options 28:15 Compounding Pharmacies: Pros and Cons 29:58 The Risks of Compounded Medications 34:22 The Social Implications of Weight Loss Drugs 39:33 Long-Term Use and Ethical Considerations RESOURCES MENTIONED: 🟡 The Ozempic Revolution: Exploring the Soaring Popularity of GLP-1 Drugs https://www.buzzsprout.com/2171581/episodes/12924933 🟡 What are "GLP1 Agonists"? https://glp1.guide/content/what-are-glp1-agonists/ 🟡 GLP‐1 signaling in the brain https://pmc.ncbi.nlm.nih.gov/articles/PMC8820188/?ref=glp1.guide 🟡 FDA’s ongoing evaluation of reports https://www.fda.gov/drugs/drug-safety-and-availability/update-fdas-ongoing-evaluation-reports-suicidal-thoughts-or-actions-patients-taking-certain-type?ref=glp1.guide 🟡 Drug ad spending https://www.cnbc.com/2024/04/03/weight-loss-diabetes-drug-ad-spending-tops-1-billion.html 🟡 GLP-1 Adverse Events https://www.mdpi.com/1424-8247/17/2/199?ref=glp1.guide 🟡 FDA’s Concerns with Unapproved GLP-1 Drugs Used for Weight Loss https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/fdas-concerns-unapproved-glp-1-drugs-used-weight-loss 🟡 Once-Weekly Semaglutide in Adults with Overweight or Obesity https://www.nejm.org/doi/full/10.1056/NEJMoa2032183 🟡 The New Yorker https://www.newyorker.com/magazine/2023/03/27/will-the-ozempic-era-change-how-we-think-about-being-fat-and-being-thin Listen to our How to Fitness podcast on your favorite platform! https://howtofitness.buzzsprout.com/2171581/episodes We’d love to hear your thoughts! Share your feedback or questions in the comments below! And while you’re here, don’t forget to subscribe to our podcast and hit that notification bell so you never miss an episode. STAY CONNECTED 🟡 Michael Ulloa: https://www.michaelulloa.com/ Instagram: https://www.instagram.com/michaelulloapt 🟡 Kate Lyman: https://www.katelymannutrition.com/ Instagram: https://www.instagram.com/klnutrition/ Thank You for Listening to How to Fitness Podcast with Michael Ulloa and Kate Lyman! #howtofitness #howtofitnesspodcast #healthandfitnesspodcast #bustingnutritionmyth
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PuraVive presents a natural blend comprising eight pharmaceutical ingredients, all carefully chosen to contribute to the process of weight loss. The product is meticulously packaged in high-quality plastic bottles to ensure its integrity. At the heart of the PuraVive formula lies the intriguing discourse on "white fat" versus "brown fat." The product's foundation is rooted in the belief that elevating brown fat levels may hold the key to promoting effective weight loss.
Numerous studies support the notion that lean individuals tend to possess higher levels of brown fat, while those who are obese typically exhibit lower levels. However, inducing a shift in the body's fat production towards brown fat necessitates significant metabolic changes. PuraVive steps in as a solution, aiming to facilitate this transition.
PuraVive asserts that its natural ingredients work synergistically to dissolve stubborn fat deposits, utilizing them as fuel for various bodily functions. The supplement aims to regulate appetite, maintain steady energy levels, and alter the body's storage mechanisms for newly produced fat cells. As these processes unfold concurrently, the body gradually accumulates dietary fat in the form of brown fat.
✅Puravive Ingredients
Holy Basil (Tulsi)
A treasured entity in the world of Ayurvedic medicine, Holy Basil, often dubbed Tulsi, has transcended the confines of traditional medicine, finding validation in modern scientific research. Renowned for its ability to mediate appetite hormones like ghrelin and leptin, it can curb those nagging hunger pangs, fostering satiety.
Propolis
The dedication of bees extends beyond honey. They produce propolis, a natural sealant for their hives, offering protection against microbial intruders. The real magic of propolis, however, unfurls in its ability to modulate lipid metabolism, crucial for weight control. Extensive research has illuminated its potential in managing cholesterol and triglycerides, underscoring its significant role in a holistic health approach.
Oleuropein
Delving into the metabolic realm, oleuropein emerges as a heavy lifter. Its prowess lies in activating energy-dissipating proteins in mitochondria and hampering the creation of new fat cells. This double-edged sword not only amplifies calorie burning but also curtails the accumulation of fat, painting a promising picture for weight management aficionados.
White Korean Ginseng
With roots in traditional medicine, this ginseng variant has displayed an uncanny knack for interfering with fat storage mechanisms. Its influence on molecular players like PPARγ and C/EBPα can thwart excessive fat deposition, fostering a desirable, leaner body silhouette.
Luteolin
Beyond its vibrant hue, luteolin emerges as a guardian against cellular disruptions, especially the mTOR pathway, which, when astray, can spell metabolic chaos. By anchoring this pathway, luteolin can modulate appetite, curbing caloric intake. Its portfolio doesn’t stop there – boasting anti-inflammatory and antioxidant capacities, it champions overall metabolic health.
Amour Cork Bark
A relatively unsung hero, this bark is a powerhouse in ensuring a harmonious digestive orchestra. Its benefits are manifold, from offering respite from bloating to nurturing vital organs like the heart and liver. In the wellness odyssey, this bark ensures each step is grounded in holistic health.
Quercetin
This plant-sourced flavonoid wears many hats. Its star-studded resume includes maintaining circulatory equilibrium and guarding against age’s relentless march. On the weight loss frontier, Quercetin lends its metabolic prowess, amplifying the body’s innate fat-burning processes.
Kudzu Root
Rich in antioxidants, Kudzu Root is a natural sentinel against cellular marauders, promoting overall vitality. Its cardiovascular benefits are noteworthy, but in the realm of weight management, it’s its potential to elevate BAT levels that truly captures attention.
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00:00 Introduction
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01:40 Does it Work for Weight Loss?
02:34 Ingredients and benefits
03:01 How to use Puravive
03:32 How does Puravive Work
05:00 Conclusion
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Are There Supplements That Can Help Manage Gluconeogenesis On Keto? In this informative video, we will discuss the role of gluconeogenesis in the context of a ketogenic diet. Understanding how your body produces glucose from non-carbohydrate sources is essential for anyone following keto, especially if managing blood sugar is a concern. We will clarify how gluconeogenesis works and why it is not easily influenced by dietary changes or supplements. Many people on keto worry about the impact of gluconeogenesis on their blood sugar levels and ketosis. We will explore the relationship between protein intake and gluconeogenesis, highlighting that the body's demand for glucose is the primary driver of this process. Additionally, we will touch on the current state of supplements that claim to affect gluconeogenesis and clarify their effectiveness. For those with diabetes, monitoring blood sugar levels is crucial while on a ketogenic diet. We will emphasize the importance of balanced nutrition and working with healthcare professionals to address individual health needs. Join us for this enlightening discussion as we navigate the complexities of gluconeogenesis and its relevance to your ketogenic journey. Don't forget to subscribe to our channel for more useful tips and information on maintaining a successful keto lifestyle. ⬇️ Subscribe to our channel for more valuable insights. 🔗Subscribe: https://www.youtube.com/@KetoKitchenHQ/?sub_confirmation=1 #KetoDiet #Gluconeogenesis #BloodSugar #Ketosis #ProteinIntake #KetoSupplements #DiabetesManagement #MetabolicHealth #InsulinSensitivity #HealthyEating #NutritionTips #KetoLifestyle #DietaryGuidance #HealthAndWellness #KetoCommunity About Us: Welcome to Keto Kitchen HQ, your go-to channel for everything related to the keto diet. Whether you're a beginner looking to understand Keto Diet Basics or an experienced practitioner refining your approach, we cover a range of topics including Low-Carb Meal Planning, Ketosis Explained, and Keto-Friendly Foods. Our engaging videos will help guide you on your journey with insights into Intermittent Fasting, Keto for Weight Loss, and delicious Ketogenic Recipes.
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