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Partial or biased agonism to improve GLP-1 receptor agonist properties by Ben Jones, Clinical Senior Lecturer Imperial College London I will discuss our work aiming to understand whether the therapeutic properties and side effect profile of GLP-1R agonism can be improved by refining intracellular signalling properties. Ben Jones is a Clinical Senior Lecturer within the Section of Endocrinology and Investigative Medicine, and a Consultant in Metabolic Medicine based in Imperial College Healthcare NHS Trust and North West London Pathology. His research is focused on the translational pharmacology of G protein coupled receptors in metabolic disease. He completed his undergraduate medical training at the University of Cambridge in 2006, and was a Foundation and Core Medical trainee on the Cambridge and Oxford rotations, respectively. In 2010 he moved to Imperial as an Academic Clinical Fellow in Metabolic Medicine. He was awarded an MRC-funded Clinical Research Training Fellowship in 2013 (supervisors: Prof Steve Bloom and Prof Tricia Tan), during which he applied the emerging concept of "biased agonism" to the GLP-1 receptor. After completing clinical training in 2020 he has was awarded the Imperial Post-Doctoral, Post-CCT Fellowship (IPPRF), and subsequently an MRC Clinician Scientist Fellowship. Current work aims to establish the mechanism of action of “biased” incretin receptor agonists, and how their unusual effects can be exploited therapeutically in diabetes and obesity. https://thelongevityforum.com
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A video summary from the original blog "Semaglutide and Gastric Bypass: Your Ultimate Guide to Maximizing Weight Loss" published here: https://bmidoctors.com/semaglutide-and-gastric-bypass-your-ultimate-guide-to-maximizing-weight-loss/
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Do this at home workout to get a smaller waist and lose belly fat in 14 days. No equipment needed. I will show you easy and intense exercises for how to lose belly fat and small waist from home. Do this workout challenge for 14 days to see results! Beginner modifications included. Day 23 of the 40 Day Summer Shred Challenge 🌎 HOW TO SIGN UP? 1. Get your FREE 40 Day Workout Calendar with daily workouts from: https://www.leanwithlilly.com 2. A new workout will be uploaded every day at 8pm GMT 3. The other workouts to compliment each new workout can be found in your FREE 40 Day Planner 🥳 GIVEAWAYS EVERY WEEK! There will be a winner EVERY 7 DAYS! From winning cute sports outfits to my very own #LWL resistance bands and cook book To Enter 1. Tag me in your instagram stories @lillysabri 2. #LWL40DayShred That's it! A new winner will be announced every Wednesday in my Video upload (this will not be one of the workout videos- it will be my vlog uploads, so keep your eyes peeled) Who's in? #LetsDoThis xx Love Lilly XX 🔥 Shop my LEAN Guide & Bands here: https://www.leanwithlilly.com 💙 FOLLOW ME: Instagram: https://instagram.com/lillysabri Private Facebook Group- Lean with Lilly Guides https://www.facebook.com/groups/50873... Twitter: https://twitter.com/lillysabri Facebook: https://www.facebook.com/lilly.sabri/ Check out my website for blogs & loads of yummy recipes https://www.leanwithlilly.com ___________________________________________________________________ 🔔 DON'T FORGET to Subscribe for daily uploads xx Hit that bell icon to get a notification every time I upload. 20% OFF ALL OPTIMUM NUTRITION PRODUCTS 'lillysabri20' on Check Out https://www.optimumnutrition.com/en-gb
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