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To cite: Senni N, Savall M, Cabrerizo Granados D, et al. Gut 2019;68:322-334. Read the full article here: http://dx.doi.org/10.1136/gutjnl-2017-315448. Objectives: CTNNB1-mutated hepatocellular carcinomas (HCCs) constitute a major part of human HCC and are largely inaccessible to target therapy. Yet, little is known about the metabolic reprogramming induced by β-catenin oncogenic activation in the liver. We aimed to decipher such reprogramming and assess whether it may represent a new avenue for targeted therapy of CTNNB1-mutated HCC. Conclusions: FAO induced by β-catenin oncogenic activation in the liver is the driving force of the β-catenin-induced HCC. Inhibiting FAO by genetic and pharmacological approaches blocks HCC development, showing that inhibition of FAO is a suitable therapeutic approach for CTNNB1-mutated HCC.

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This intense abs workout is going to be slow and controlled with the movements. It’s just a 5 minute workout, but you are going to feel the burn in your core. These abs exercises will help show you how to lose belly fat and get a flat stomach at home. For the best and fastest results, be sure to combine this workout with my fat burn workouts and good nutrition. 🔥 Get the LEAN App 🔥 Personalised workout programs, personalised meal plans, exclusive workout challenges, a habit tracker, a journal, a recipe library and so much more. Get the LEAN App here: https://www.leanwithlilly.com/ 👩‍🎓 Students get 20% off the LEAN App and Products here: https://www.leanwithlilly.com/student 🥤 The supplements & protein bars I use to get results: https://www.leanwithlilly.com/pages/supplements 💪 Get your Free Home Workout programs here: https://www.leanwithlilly.com 🤍 FOLLOW ME: Instagram: https://instagram.com/lillysabri TikTok: https://www.tiktok.com/@lillysabri?lang=en Private Facebook Group- Lean with Lilly Guides https://www.facebook.com/groups/508730913266325/ Twitter: https://twitter.com/lillysabri Facebook: https://www.facebook.com/lilly.sabri/ 🔔 DON'T FORGET to Subscribe for daily uploads xx Hit that bell icon to get a notification when I upload. 0:00 Abs Workout Introduction 0:07 Your Abs Workout Results 0:18 Get Results With LEAN 0:29 Lose Belly Fat Workout 5:32 Complete Exercise Get love nwantiti (ah ah ah) by Ckay here https://t.lickd.co/8fb8a6fb7ad14df4940f4cefec53c606 License ID: N941JPE5z8m Get Life Goes On by Oliver Tree here https://t.lickd.co/2672ea6e116e47e6bb7e06582d7c53cb License ID: OW5m5JpNgLG Get this and other songs for your next YouTube video at https://lickd.co/r/lillysabri Disclaimer: Please remember that we cannot spot reduce fat, meaning we can’t choose the areas on our body where we loose fat. However to get fat loss results I recommend the following: 1. Being in calorie deficit 2. Cardio/ HIIT workout (I often call these Fat Loss/Burn workouts on my channel) 3. Resistance training and specific muscle targeted workouts. To strengthen and develop specific muscles. I have hundreds of other home workouts available on my channel, so you can pick and choose which workouts you want to do, to not only make you build a strong body, but also feel amazing. Please remember every body is different and we all progress at different rates. The fact that you have shown up and completed this workout is incredible. You should be very proud of yourself for taking the steps to improve not only your physical, but also your mental health. The key to achieving your fitness and health goals is consistency and healthy lifestyle changes, without restriction. I don’t believe in crazy fad diets. Simply eat nutritious food, move your body, smile and enjoy the journey! Love Lilly

How Did Kelly Clarkson Lose All That Weight What Is Kelly Clarkson Doing To Lose Weight

When it comes to losing weight, many people look to celebrities for inspiration. Kelly Clarkson, who has been open about her weight struggles in the past, recently revealed her incredible weight loss transformation. Fans are curious about what methods she used to achieve such impressive results. In this article, we take an inside look at what Kelly Clarkson took to lose weight and how it has helped her on her journey to a healthier lifestyle.

The Beginning of Kelly Clarkson’s Weight Loss Journey

Before diving into what Kelly Clarkson took to lose weight, it’s important to understand where her journey began. The Grammy-winning singer has always been open about her struggles with weight and body image. In interviews, she has spoken about how her weight has fluctuated over the years and the challenges she has faced in maintaining a healthy lifestyle.

After giving birth to her two children, Kelly Clarkson found herself at a weight that she was unhappy with. She knew that she needed to make a change for both her physical and mental well-being. This realization marked the start of her weight loss journey, and she was determined to take control of her health.

Like many people, Kelly Clarkson turned to a combination of diet and exercise to help her lose weight. She knew that there was no quick fix or miracle solution, and that sustainable weight loss would require commitment and dedication. With the help of professionals, she developed a plan that would work for her and her lifestyle.

Kelly Clarkson’s Diet Plan

One of the key components of Kelly Clarkson’s weight loss journey was her diet plan. She worked closely with a nutritionist to create a meal plan that was both healthy and sustainable. Instead of following a restrictive diet, Kelly focused on eating whole, nutrient-dense foods that would fuel her body and support her weight loss goals.

Some of the foods that Kelly incorporated into her diet plan included lean proteins, fruits and vegetables, whole grains, and healthy fats. She also made sure to stay hydrated by drinking plenty of water throughout the day. By making smart food choices and paying attention to portion sizes, Kelly was able to see progress on the scale and feel better overall.

Another important aspect of Kelly Clarkson’s diet plan was moderation. She didn’t deprive herself of the foods she loved, but instead learned how to enjoy them in moderation. By allowing herself the occasional treat or indulgence, Kelly was able to stick to her diet plan long-term without feeling restricted or deprived.

Kelly Clarkson’s Workout Routine

In addition to her diet plan, Kelly Clarkson also incorporated a workout routine into her weight loss journey. She worked with a personal trainer to develop a fitness plan that would help her reach her goals and improve her overall health. Kelly’s workout routine included a mix of cardio, strength training, and flexibility exercises.

Some of the exercises that Kelly enjoyed included running, weightlifting, yoga, and dance. By mixing up her workouts and trying new activities, she was able to stay motivated and engaged in her fitness journey. Kelly made sure to schedule regular exercise sessions into her busy schedule, prioritizing her health and well-being.

Consistency was key for Kelly Clarkson when it came to her workout routine. She made exercise a non-negotiable part of her daily routine, finding ways to stay active even on the busiest of days. By staying committed to her fitness plan, Kelly was able to see improvements in her strength, endurance, and overall fitness level.

Results and Reflections

After months of hard work and dedication, Kelly Clarkson has achieved incredible results on her weight loss journey. Fans have been amazed by her transformation and inspired by her commitment to health and wellness. By focusing on a balanced diet, regular exercise, and a positive mindset, Kelly has been able to find success in her weight loss efforts.

Looking back on her journey, Kelly Clarkson has expressed gratitude for the support and encouragement she has received from fans and loved ones. She has also shared how her weight loss has impacted her confidence, energy levels, and overall quality of life. Kelly’s journey serves as a reminder that with determination and perseverance, anything is possible.

As Kelly Clarkson continues on her path to health and happiness, fans can’t help but wonder what the future holds for the talented singer. One thing is for certain – Kelly’s weight loss journey is far from over, and she remains committed to living her best life both on and off the stage. With her positive attitude and never-give-up spirit, Kelly Clarkson is sure to inspire others to take control of their health and make positive changes in their own lives.

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Find Tech & Science Daily wherever you find your podcasts, or via this link: https://lnk.to/x494eZ Rachelle Abbott joins London GP Dr Sonia Adesara, who explains the ‘wild west’ culture of online weight-loss jab prescriptions. Plus Louise Edwards, chief strategy officer & deputy registrar at the General Pharmaceutical Council, on tougher new rules to combat unregistered online pharmacies. Endangered Darwin’s froglets, the size of a grain of rice, born at London Zoo - with Dr Ben Tapley, ZSL’s curator of amphibians and reptiles. How AI helped The Beatles secure their eighth Grammy Award. Also in this episode: Major AI breast cancer screening trial ‘to cut waiting times’ Source Code by Bill Gates: Microsoft co-founder believes he would have been diagnosed with childhood autism Could You Be Loved named Bob Marley’s most played track in UK this century Subscribe to the Evening Standard: https://bit.ly/Subscribe-to-Evening-Standard for latest breaking news from the UK, US and around the world, plus podcasts and features. Evening Standard on socials: Check out our full video catalog: https://www.youtube.com/c/LondonEveningStandard/videos Videos, daily editorial and more: https://www.standard.co.uk/ Like us on Facebook: https://www.fb.com/eveningstandard Follow us on Twitter: https://twitter.com/eveningstandard and Instagram: https://www.instagram.com/evening.standard

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http://podcast.drpompa.com/ Cellular Healing TV Episode 43: Losing Fat & Improving Health with Phil Kaplan Notice: Dr. Daniel Pompa is licensed by the Pastoral Medical Association (PMA). For detailed licensing & disclaimer information, visit: http://drpompa.com/pma-disclaimer Dr. Pompa has voluntarily relinquished his chiropractic license in the state of Pennsylvania in order to more effectively pursue his dream of world health.

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Learn how to cut fat without losing muscle in this comprehensive guide! Whether you’re prepping for summer, a photoshoot, or just trying to hit your fitness goals, this video will cover everything you need to know. From setting up a proper caloric deficit to optimizing your workouts and cardio, we’ll dive into actionable strategies that actually work. Plus, find out whether fasted cardio is worth it, how to prevent muscle loss, and the best ways to structure your diet. Perfect for beginners and experienced lifters alike! 💡 Key Tips You’ll Learn: • How to calculate your calorie needs for fat loss. • The importance of protein, carbs, and fats during a cut. • Why strength training is critical for muscle retention. • Effective cardio strategies for maximizing fat loss. 👉 Don’t forget to like, comment, and subscribe for more hypertrophy, fitness, and nutrition tips from 88 Fitness Training! #CuttingPhase #FatLossTips #LoseFatKeepMuscle #HypertrophyTraining #FastedCardio #HIITvsLISS #CaloricDeficit #StrengthTraining #FitnessMotivation #CuttingDiet #CardioForFatLoss #FatLossJourney #MuscleRetention #WeightLossTips #88FitnessTraining #BodyRecomposition #NutritionTips #FitnessLifestyle

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As the popularity of the ketogenic diet continues to rise, so does the demand for quality keto supplements. One product that has been gaining attention in the keto supplement market is Kwazi Keto Gummies. These gummies are a convenient and delicious way to incorporate exogenous ketones into your daily routine, making it easier to stay in ketosis and achieve your weight loss goals.

The Benefits of Kwazi Keto Gummies

Kwazi Keto Gummies are infused with exogenous ketones, which can help your body enter a state of ketosis more quickly. This means that your body will start burning fat for fuel instead of carbs, making it easier to reach your weight loss goals. In addition to aiding in weight loss, exogenous ketones can also provide a steady source of energy, improve cognitive function, and enhance athletic performance.

One of the main benefits of Kwazi Keto Gummies is their convenience. Unlike other keto supplements that come in powder or pill form, these gummies are easy to take on the go. You can keep a bottle in your purse or gym bag for a quick and tasty energy boost whenever you need it.

Another advantage of Kwazi Keto Gummies is their delicious taste. These gummies come in a variety of flavors, such as raspberry lemonade and watermelon, making them a enjoyable way to satisfy your sweet tooth while staying in ketosis. Whether you have a busy schedule or simply want a guilt-free treat, these gummies are sure to please your taste buds.

How to Incorporate Kwazi Keto Gummies into Your Routine

One way to incorporate Kwazi Keto Gummies into your daily routine is to take them as a pre-workout supplement. The exogenous ketones in these gummies can provide a quick source of energy to fuel your workout, helping you push through those tough gym sessions. You can also take them as a mid-day pick-me-up to combat that afternoon slump and stay focused and alert.

Another way to use Kwazi Keto Gummies is to include them as part of your ketogenic meal plan. You can enjoy a couple of gummies before a meal to help suppress your appetite and prevent overeating. This can be especially helpful if you’re trying to stick to a calorie deficit for weight loss.

If you’re following a strict ketogenic diet, you can also use Kwazi Keto Gummies as a dessert substitute. Instead of reaching for high-carb sweets, you can indulge in a few gummies to satisfy your cravings without derailing your progress. This can make it easier to stick to your diet and see results faster.

Are Kwazi Keto Gummies Right for You?

Before adding Kwazi Keto Gummies to your supplement routine, it’s important to consider your individual goals and needs. If you’re looking for a convenient and tasty way to support your ketogenic lifestyle, these gummies could be a great fit for you. However, if you have any underlying health conditions or concerns, it’s best to consult with a healthcare professional before trying any new supplement.

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Overall, Kwazi Keto Gummies offer a convenient, delicious, and effective way to incorporate exogenous ketones into your daily routine. Whether you’re looking to boost your energy levels, enhance your mental clarity, or accelerate your weight loss, these gummies can help you reach your goals and stay on track with your ketogenic diet. Give them a try and see the benefits for yourself!