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An oral option of the GLP-1 weight loss drug could be on the horizon. In this "The Doc Is In" segment, Emergency Physician, Dr. Ryan Stanton, tells us how drug manufacturers Eli Lilly and Novo Nordisk, have trials ongoing for an oral GLP-1 version. "The Doc Is In" is produced for Everyday Medicine by Go Media Kentucky.
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Weight loss is a common goal for many individuals looking to improve their overall health and well-being. While diet and exercise are often key components of any weight loss plan, some individuals may benefit from additional support in the form of medications or supplements. One such medication that has gained popularity in recent years is semaglutide. Originally developed as a treatment for type 2 diabetes, semaglutide has also been found to be effective in promoting weight loss in individuals with or without diabetes.
The Science Behind Semaglutide for Weight Loss
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that works by mimicking the effects of incretin hormones in the body. Incretin hormones help regulate insulin secretion, glucose levels, and food intake. By activating the GLP-1 receptor, semaglutide can help reduce appetite, increase feelings of fullness, and slow down digestion, all of which can contribute to weight loss.
In clinical trials, semaglutide has been shown to significantly reduce body weight when used in conjunction with a reduced-calorie diet and increased physical activity. Studies have demonstrated that individuals taking semaglutide experienced greater weight loss compared to those taking a placebo. In addition to weight loss, semaglutide has also been shown to improve other markers of health, such as blood pressure, cholesterol levels, and blood sugar control.
One of the key advantages of semaglutide is its long-acting formulation, which allows for once-weekly dosing. This can make it a more convenient option for individuals who may have difficulty remembering to take daily medications. However, it is important to note that semaglutide is not a magic bullet for weight loss and should be used in conjunction with lifestyle changes to achieve and maintain long-term success.
Best Practices for Using Semaglutide for Weight Loss
Before starting semaglutide or any other weight loss medication, it is important to consult with a healthcare provider to determine if it is a safe and appropriate option for you. Your healthcare provider can assess your individual health needs and goals and help create a personalized plan for weight loss. They can also monitor your progress and make any necessary adjustments to your treatment plan.

When taking semaglutide for weight loss, it is important to follow the dosing instructions provided by your healthcare provider. This may involve starting with a lower dose and gradually increasing it over time. It is also important to continue following a healthy diet and engaging in regular physical activity to maximize the benefits of semaglutide.
Some common side effects of semaglutide may include nausea, vomiting, diarrhea, and constipation. These side effects are typically mild and tend to improve over time as your body adjusts to the medication. If you experience persistent or severe side effects, be sure to contact your healthcare provider for further guidance.
FAQs about Semaglutide for Weight Loss
Q: How long does it take to see results with semaglutide for weight loss?
A: Results may vary, but many individuals start to see improvements in weight loss within the first few weeks of starting semaglutide. It is important to be patient and consistent with your treatment plan to achieve long-term success.
Q: Is semaglutide safe for long-term use?
A: Semaglutide has been shown to be safe and effective for long-term use in clinical trials. However, it is important to continue monitoring your health and working closely with your healthcare provider to ensure its safety and efficacy for you.
Q: Can anyone take semaglutide for weight loss?
A: Semaglutide may not be suitable for everyone, so it is important to consult with a healthcare provider to determine if it is a safe and appropriate option for you. Individuals with a history of pancreatitis or thyroid cancer may not be able to take semaglutide.
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So Boris Johnson says he’s given up his weight-loss jabs — didn’t like how they made him feel. Honestly? Fair enough, BoJo. We’re living in a time where: 💉 We were once terrified of COVID vaccines… 🌱 But now jabbing ourselves for thinness is “brave” 🍫 Chocolate buttons are a crime, but Ozempic’s a lifestyle 📱 Celebs are proudly telling us they lost weight with meds 👧 And meanwhile we’re telling our kids: “don’t do drugs, don’t vape, don’t smoke.” Where’s the logic? I’m over it. I’ve got hips made for the 1940s and a sweet tooth from the 90s. And if Boris Johnson wants to worry about anything, it’s not his waistline — it’s his 10 kids and cocktails in Capri. Let’s be kinder to ourselves. Embrace our bodies. And maybe… just eat fewer chocolate buttons. Or not. 💁♀️ #OzempicRant #BoJoOnTheJab #WeightLossMadness #ThinIsNotTheGoal #RealBodyTalk #BodyPositivity #ChocolateButtonsWin #CelebCultureFail #BeKindToYourself #ScrewTheStandards #MumRant #TikTokRealTalk #InjectingThinness #1940sHipsClub #HonestParenting
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The truth about weight loss on GLP-1: three mistakes could be holding you back. 🫣 Protein shakes? They spike blood sugar and increase hunger - opt for whole proteins like chicken or eggs. Consistency is key, and don’t overdo it at the gym, walking is your friend. #weightlossmistakes #glp1diet #sustainablefitness
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This video dives into the emotional side of being on a GLP1 medication and body dysmorphia and how much we think all of this will change on a GLP1. #glp1 #ZEPBOUND #bodydysmorphia #glp1community #glp1journey ourney
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Can therapeutic nutritional ketosis (aka a keto diet) help with tapering psychiatric medications in conditions like bipolar disorder, depression, schizophrenia, anxiety, or other psychiatric illness? Can you decrease or even stop taking some or all of your medications? There is no universal answer to this question; it depends on the individual. Psychotropic medications are typically first-line therapy for treating serious mental illness and can be life-saving. But over time, medications alone may not be completely effective in treating symptoms. And especially at high doses, they can come with problematic side effects. Metabolic nutritional therapy, specifically with nutritional ketosis, can add another treatment layer and may help promote cognitive function, mood stability and energy and overall functioning. Anecdotal evidence and growing numbers of case reports show that nutritional ketosis can help people be well enough to consider lowering the doses and number of their medications. That said, we cannot stress enough that it is essential that anyone considering reducing their medications work with their prescribing clinician, whether or not they are using nutritional ketosis as a treatment strategy. Table of Contents: 0:00 - Introduction 3:45 - Interview with Dr. Georgia Ede 32:16 - Interview with Matt Baszucki 53:59 - Conclusion Experts featured in this video: Georgia Ede, MD - www.diagnosisdiet.com Twitter @GeorgiaEdeMD Ketogenic Diets and Psychiatric Medications https://www.psychologytoday.com/us/blog/diagnosis-diet/201803/ketogenic-diets-and-psychiatric-medications Matt Baszucki, co-host of Bipolarcast on YouTube Bipolarcast Episode 1: Interview with Matt Baszucki on Ketogenic Diet and Bipolar Disorder https://www.youtube.com/watch?v=zNI8asTF5w8&t=2s Study Referenced: The Ketogenic Diet for Refractory Mental Illness: A Retrospective Analysis of 31 Inpatients https://pubmed.ncbi.nlm.nih.gov/35873236/ Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind™ is a nonprofit initiative incubated by Baszucki Group. Our mission is to provide education and resources in the emerging field of metabolic psychiatry, including ketogenic interventions for mental disorders. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #MedicationReduction #BipolarTreatment #MetabolicNeuroscience #KetogenicMetabolicTherapy #DepressionTreatment #NutritionalKetosis #MentalIllnessTreatment #MentalHealthIsMetabolicHealth #BipolarDiet #TaperingPsychiatricMedications #TaperMeds #KetoTaperingMeds #KetoPsychMeds #TaperMedsBipolar #TaperDepressionMeds
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