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In this video we will cover everything you need to know about Sildenafil, also known as Viagra. We will discuss how and when to use it, we will cover its side effects, dosage and much, much more. This video is part of a videoseries on sex and urinal tract related medical problem. Find the playlists here: https://www.youtube.com/playlist?list=PLaG3Bo3L0gX6I4FYPkL6bJ1Xx7dRs697P Generic name: Sildenafil. Brand names: Viagra, Revatio or Balcoga. Available as a tablet, suspension and injection. How to use it? - Tablet or capsule: Just swallow it with half a glass of water. - Suspension: first shake the bottle for 10 seconds. Then measure the correct amount with a dosing syringe or measuring cup and take the dose. Then rinse the dosing syringe or measuring cup with water and drink this water as well. - Injection: your doctor or nurse will administer it to you. How does it work? Sildenafil is part of a group of drugs which inhibit the enzyme PDE-5. This enzyme is normally responsible for the breakdown of cGMP. cGMP is generated in the shaft of the penis through stimulation. When using Sildenafil the concentration of cGMP in the shaft is increased. This causes the smooth muscles in the penis to slacken, allowing it to fill with blood. Creating an erection. cGMP also plays a role in the vascular system of your lungs. There is also relaxes the smooth muscles, resulting in vasodilation and decreasing the blood pressure. What is the correct dosage? The precise dose will depend on your specific indication of use, the side effect you might experience and the severity of your symptoms. Therefore always use the precise amount and frequency your doctor prescribed you. - However, when treating erectile dysfunction, most doctors will start with an initial dose of 50 mg approximately 1 hour prior to sexual activity, no more than 1×/day. It is important to note, that this drug does require sexual activity in order to work properly. Based on the effectiveness you experience and your tolerance, the dose might be adjusted to 25 to max. 100 mg 1x/day. - When treating pulmonary hypertension the usual dose is 20 mg 3×/day, to be taken at 6–8 hour intervals. What are the side-effects? - The following side effects are seen when using sildenafil to treat erectile dysfunction: Common (1-10%): Dizziness, flushing, hot flashes, nausea, blurred vision and nasal congestion. Uncommon (0.1-1%): Hypersensitivity reactions, palpitations, fast heartbeat, chest pain, high blood pressure, low blood pressure, drowsiness, fatigue, dizziness, tinnitus, nosebleed, dry mouth, vomiting, abdominal pain and muscle aches. Rare (0.01-0.1%): fainting, stroke, myocardial infarction, palpitations, chest pain, sudden cardiac death, irritability, penile hemorrhage, deafness, dry nose, eye hemorrhage, impaired vision and several other significant side effects. The following side effects are seen when using sildenafil to treat pulmonary hypertension: Very common (10%) headache, flushing, diarrhoea, pain in arms or legs. Common (1-10%): Dizziness, tremor, inflammation of the nose/sinuses/lungs, cough, nasal congestion, nosebleed, fever, muscle pain, migraine, insomnia, anxiety, haemorrhoids, dry mouth, night sweats, blurred vision, and eye bleeding . Uncommon (0.1–1%): blood in urine, penile bleeding, breast growth and blood in semen. Safety: - The usage of sildenafil can lead to dizziness or fatigue. Please do not drive while experiencing this. - Furthermore, alcohol increases erectile dysfunction. Therefore make sure to avoid it. sildenafil can also have interactions with other drugs your are taking. Always discuss this with your prescribing doctor. - Lastly, Sildenafil could be dangerous for pregnant women and women who are breastfeeding. Therefore always discuss this with your personal doctor. - Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor. - Literature: 1: Farmacotherapeutisch Kompas. (2022). Sildenafil. 2: Apotheek.nl (2022). Sildenafol. * The images in this video are used for educational purposes only. Most of the images and videos in this video come from https://www.canva.com/. Follow me on instagram: @HOWTOMEDICATE Follow me on twitter: @HOWTOMEDICATE Support me on Patreon: https://www.patreon.com/howtomedicate

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Hello! Before we dive into the topic, don't forget to subscribe to the channel, like, share and leave your comment! Now, we will clarify your doubts in a simple and educational way about one of the most well-known medications for treating erectile dysfunction: Viagra. Viagra, or sildenafil, is a medication widely used by men looking to improve their quality of sexual life. But do you know exactly how it works? Or what is the best way to use it? In this text, we will explain what Viagra is, its active ingredient, the available presentations, and the indications for responsible and effective use. Stay tuned to the end to understand when and how to take it, whether it can be used every day, and what is the ideal dose to obtain the best results. Viagra, a widely known medication for treating erectile dysfunction, is available in different concentrations. Among them, we have doses of 25 mg, 50 mg and 100 mg, with the latter being the maximum recommended dose for daily use. It is important that the ideal dosage be prescribed by a healthcare professional, taking into account the needs and characteristics of each patient. But how does sildenafil, the active ingredient in Viagra, work in the body? This compound acts by selectively blocking the enzyme phosphodiesterase type 5 (PDE5), found in the penis. Inhibiting this enzyme allows the arteries to relax and the blood vessels to dilate, facilitating the entry of blood into the tissues and, consequently, promoting an erection. To better understand, let's analyze what happens during this process. Imagine a penis in a relaxed state and, next to it, an erect penis. Internally, the structure of the penis is composed of two areas called corpora cavernosa, which look like small spaces or caverns. In the relaxed state, the arteries inside these corpora cavernosa are contracted, restricting blood flow. When there is sexual stimulation and sildenafil is present in the body, the arteries dilate, allowing blood to fill these cavernous spaces. This increase in blood flow is what makes the penis rigid, resulting in an erection. This mechanism of action is what makes Viagra an effective tool in the treatment of erectile dysfunction, helping many men regain their confidence and quality of life. But if we now look at the other drawing and compare it, we see that when there is an erection, the arteries here are large, they are dilated and open, a lot of blood enters and thanks to this, the erection of the penis is achieved. When we take Viagra, sildenafil blocks the enzyme phosphodiesterase, this helps to open the arteries of the penis and, thus, facilitates and improves the erection, monitoring the onset and duration of the effects. When should I take sildenafil? Should it be taken before sexual activity and on an empty stomach? Stomach and because it is a water-soluble medication, it is advisable to swallow it along with a glass of water to facilitate its absorption, onset of effects from the moment you take it, it takes on average 30 minutes to start taking effect, that is, you have to take it 30 minutes before sexual activity, maximum effect, is maximum concentration in the blood and therefore both, its maximum effect is achieved one hour after dosing. And how long do its effects last: The drug will be in the blood circulating through your body. That is, for 6 hours, you will have an easy erection in gel preparations. Liquid or spray are absorbed even faster interaction with food, as we just mentioned, sildenafil should be taken on an empty stomach and sildenafil Viagra interacts with almost all foods, especially with fatty foods and alcohol when the sildenafil medication is taken with food, the absorption speed is reduced, that is, it takes longer to start taking effect. With a delay of one hour to reach maximum plasma concentrations, the duration of the effect also decreases. But less and also in terms of the quality or rigidity of the erection, its potency decreases with a reduction in the maximum concentration in the blood of 29%. In other words, if you eat two hours before taking Viagra, it is as if you took less sildenafil, the food cancels out part of the Viagra. Recommended dose: How much should I take?

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Prime 25 increase penis size monthly. When you take Prime 25 formula home and use it daily and consistently, you will be providing your body with a natural help your body desperately needs to enlarge your penis size. Testosterone production and free testosterone will increase to build and maintain an adequate testosterone level and your testicular testosterone expression will increase resulting in growing the smooth muscles. The corpus cavernosum that forms most of the penis and contains blood vessels will be relaxed and highly oxygenated allowing the madly increased blood flow to fill the vessels causing a daily expansion of the spongy cylinders. That expansion will enable your body to steady widen and stretch the penis tissues to accommodate the continuous blood flow resulting in girth and length size increases. Your penis size increase will be noticeable to you and her after the first 30 days with the first enlargement phase concluded in 60 days.